The condition leads to symptoms including loss of balance, slowing of movement, difficulty moving the eyes, and dementia. Progressive supranuclear palsy radiology reference article. Mgi mouse phenotypes related to supranuclear palsy, progressive, 1. Hummingbird sign, penguin sign and mickey mouse sign. Another feature, the mickey mouse sign, describes selective atrophy of the. Progressive supranuclear palsy psp, also known as the. Discussion of difference between saccadic movement in supranuclear palsy and nystagmus. Based on the clinical and radiographic features, he was diagnosed as a case of progressive supranuclear palsy steele. Shows saccadic intrusions in forward gaze, pursuit. Progressive supranuclear palsy psp, also known as steelerichardsonolszewski syndrome, is a degenerative disease involving the gradual deterioration and death of specific volumes of the brain. Hummingbird sign, penguin sign and mickey mouse sign in progressive supranuclear palsy.
Progressive supranuclear palsy psp is a degenerative disease involving the gradual. Hummingbird sign is a rather interesting sign seen in midsagital view of mri brain in patient with progressive supranuclear palsy psp ref1. Progressive supranuclear palsy radiology reference. Psp is characterized by akinetic rigid parkinsonism, dizziness, unsteadiness, slowness, falls, and pseudobulbar dysarthria, and also supranuclear eye movement abnormalities which presented as downward, or upward, or combination gaze palsy ref2. The literature search was performed between february and may 2016. Progressive supranuclear palsy psp, also known as the steelerichardsonolszewski syndrome, is a form of parkinsonplus syndrome. Progressive supranuclear palsy psp, previously known as. Mr parkinsonism index in progressive supranuclear palsy. Pdf on nov 1, 2012, shobha m itolikar and others published hummingbird sign, penguin sign and mickey mouse sign in progressive supranuclear palsy.
One sign of psp is abnormal clumps of tau in nerve cells in the brain. Psp is the shortform of a disease called progressive supranuclear palsy. Progressive supranuclear palsy is characterized by decreased cognition, abnormal eye movements supranuclear vertical gaze palsy, postural instability and falls, as well as parkinsonian features and speech disturbances. Progressive supranuclear palsy psp is a pathologic diagnosis. Patients with psp show interesting radiological signs such as the humming bird sign and the mickey mouse sign. Progressive supranuclear palsy psp is an atypical parkinsonian syndrome characterized. Radiological biomarkers for diagnosis in psp international. Example of patient with progressive supranuclear palsy. Mickey mouse sign in progressive supranuclear palsy.
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